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. 2015 Apr 20;16(6):922–932. doi: 10.1080/15384047.2015.1040953

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Figure 1. — Anti-cancer potential of GW627368X. (A) Molecular structure of GW627368X. 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-benzeneacetamide (C₃₀H₂₈N₂O₆S). Molecular weight 544.6; λ_max: 21, 229, 295, 35 (B) Tumor bearing animals representative of each test group, (C) Excised tumor from each test group, (D) Bar graph depicting average body weight of each test group taken on day 0, 7 and 14. (E) Graph representing change in tumor volume (group average) in each test group measured every 7 days, (F) Bar graph showing average tumor mass of each test group at the end of 28 days study period. Data mean ± SD, representative of 10 animals. P < 0.05(t test), (G) Immunohistochemical analysis for expression of a) Proliferation marker, Ki67; b) Angiogenesis marker, CD31. Representative pictures taken at 20X magnification.