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. 2015 Apr 20;16(6):922–932. doi: 10.1080/15384047.2015.1040953

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Figure 4. — 28 days toxicity profile of GW627368X in mice. Bar graphs showing the levels of (A) Serum glutamic pyruvic transaminase(SGPT), Serum glutamic oxaloacetic transaminase(SGOT) and serum alkaline phosphatase(ALP) (B) Serum sodium, serum potassium (C) Serum creatinin, total uric acid, inorganic phosphate (D) Serum tryglicerides, total cholesterol (E) Conjugated and unconjugated bilirubin (F) Serum total protein, Globulin, albumin (G) Troponin in different test groups. Results represented as mean ± SD. Each bar is representative of 3 independent experiments. (H) Ex vivo spleenocyte proliferation assay. Spleenocytes isolated from animals of each test group was seeded into 96 well plate and MTT assay was performed. (I) Ex vivo culture of spleenocytes isolated from animal of each test group followed by crystal violet staining. (J) H&E stained sections of stomach and heart of animals from each test group.