Table 2.

Effect of D2R activation on rate of endocytosis of Ca_V2.2e37 splice variants and mutants

[Quin]	τ (min)
	0 nm	100 nm
37a	7.00 ± 1.23 (3)	n/a
37a + D2R	11.1 ± 1.43 (5)	6.60 ± 0.22 (3)
37b	11.6 ± 3.53 (3)	n/a
37b + D2R	29.0 ± 4.89 (4)	6.90 ± 0.36 (3)
37a L/A	13.8 ± 1.85 (4)	n/a
37a L/A + D2R	27.3 ± 4.43 (3)	18.6 ± 1.62 (3)
37a Y/A	21.1 ± 3.53 (4)	n/a
37a Y/A + D2R	12.6 ± 2.20 (3)	7.28 ± 0.90 (3)

The endocytosis time constants (τ) for Ca_V2.2 splice variants 37a and 37b and the 37a mutants, either alone or in combination with the D2R, are shown. When the D2R was included, experiments were performed in the absence (middle) or presence (right) of the D2R agonist Quin (100 nm). Number of different separate experiments are given in parentheses, with at least 20 cells per time point for each experiment.