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. 2015 Oct 26;17(Suppl 4):iv1–iv62. doi: 10.1093/neuonc/nov189

Table 2a.

Central Brain Tumor Registry of the United States (CBTRUS), Brain and Central Nervous System Tumor Histology Groupings

Histology ICD-O-3a Histology Codeb
Tumors of Neuroepithelial Tissue
Pilocytic astrocytoma* 9421, 9425c
Diffuse astrocytoma* 9400, 9410, 9411, 9420
Anaplastic astrocytoma* 9401
Unique astrocytoma variants* 9381, 9384, 9424
Glioblastoma* 9440, 9441, 9442/3d
Oligodendroglioma* 9450
Anaplastic oligodendroglioma* 9451, 9460
Oligoastrocytic tumors* 9382
Ependymal tumors* 9383, 9391, 9392, 9393, 9394
Glioma malignant, NOS* 9380, 9431c, 9432c
Choroid plexus tumors 9390
Other neuroepithelial tumors* 9363, 9423, 9430, 9444
Neuronal and mixed neuronal-glial tumors* 8680, 8681, 8690, 8693, 9412, 9413, 9442/1e,
 9492 (excluding site C75.1), 9493, 9505, 9506, 9522, 9523
Tumors of the pineal region 9360, 9361, 9362, 9395c
Embryonal tumors 8963, 9364, 9470, 9471, 9472, 9473, 9474,
 9480, 9490, 9500, 9501, 9502, 9508
Tumors of Cranial and Spinal Nerves
Nerve sheath tumors 9540, 9541, 9550, 9560, 9561, 9570, 9571
Other tumors of cranial and spinal nerves 9562
Tumors of Meninges
Meningioma 9530, 9531, 9532, 9533, 9534, 9537, 9538, 9539
Mesenchymal tumors 8324, 8800, 8801, 8802, 8803, 8804, 8805, 8806, 8810, 8815, 8824, 8830,
 8831, 8835, 8836, 8850, 8851, 8852, 8853, 8854, 8857, 8861, 8870 , 8880,
 8890, 8897, 8900, 8901, 8902, 8910, 8912, 8920, 8921, 8935, 8990, 9040, 9136,
 9150, 9170, 9180, 9210, 9241, 9260, 9373
Primary melanocytic lesions 8720, 8728, 8770, 8771
Other neoplasms related to the meninges 9161, 9220, 9231, 9240, 9243, 9370, 9371, 9372, 9535
Lymphomas and Hemopoietic Neoplasms
Lymphoma 9590, 9591, 9596, 9650, 9651, 9652, 9653, 9654, 9655, 9659, 9661,
 9662, 9663, 9664, 9665, 9667, 9670, 9671, 9673, 9675, 9680, 9684,
 9687, 9690, 9691, 9695, 9698, 9699, 9701, 9702, 9705, 9714, 9719,
 9728, 9729
Other hemopoietic neoplasms 9727, 9731, 9733, 9734, 9740, 9741, 9750, 9751, 9752, 9753, 9754, 9755,
 9756, 9757, 9758, 9760, 9766, 9823, 9826, 9827, 9832, 9837, 9860, 9861, 9866, 9930, 9970
Germ Cell Tumors and Cysts
Germ cell tumors, cysts and heterotopias 8020, 8440, 9060, 9061, 9064, 9065, 9070, 9071, 9072, 9080, 9081, 9082,
 9083, 9084, 9085, 9100, 9101
Tumors of Sellar Region
Tumors of the pituitary 8040, 8140, 8146, 8246, 8260, 8270, 8271, 8272,
 8280, 8281, 8290, 8300, 8310, 8323, 9492 (Site C75.1 only), 9582
Craniopharyngioma  9350, 9351, 9352
Unclassified Tumors
Hemangioma 9120, 9121, 9122, 9123, 9125, 9130, 9131, 9133, 9140
Neoplasm, unspecified 8000, 8001, 8002, 8003, 8004, 8005, 8010, 8021
All other 8320, 8452, 8710, 8711, 8713, 8811, 8840, 8896, 8980, 9173, 9503, 9580

aInternational Classification of Diseases for Oncology, 3rd Edition, 2000. World Health Organization, Geneva, Switzerland.

bSee the CBTRUS website for additional information about the specific histology codes included in each group: http://www.cbtrus.org.

cHistology not currently used to US cancer registration, will be included starting with diagnosis year 2015. See NAACCR website: http://www.naaccr.org/LinkClick.aspx?fileticket=4Hx-2XJJqFo%3d&tabid=161&mid=523

dMorphology 9442/3 only. 

eMorphology 9442/1 only.

*All or some of this histology is included in the CBTRUS definition of gliomas, including ICD-O-3 histology codes 9380-9384, 9391-9460.

Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NOS, not otherwise specified.