Table 26.
One-, Two-, Five- and Ten-Year Relative Survival Ratesa,b for Selected Malignant Brain and Central Nervous System Tumors by NCI Age Groups, SEER 18 Registries, 1995-2012c
| Histology | Age Group (years) | Nd | 1-Year |
2-Year |
5-Year |
10-Year |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | |||
| Pilocytic astrocytoma | Childrene (0-14) | 2,315 | 98.8 | (98.3-99.2) | 98.5 | (97.9-99.0) | 97.2 | (96.3-97.9) | 96.0 | (94.8-96.9) |
| AYAf (15-39) | 1,148 | 97.2 | (96.0-98.0) | 95.8 | (94.3-96.8) | 93.1 | (91.3-94.6) | 90.4 | (87.9-92.4) | |
| Adults (40+) | 386 | 94.9 | (91.9-96.9) | 87.5 | (83.2-90.7) | 79.4 | (73.9-83.9) | 73.3 | (66.2-79.2) | |
| Diffuse astrocytoma | Childrend (0-14) | 770 | 91.5 | (89.2-93.3) | 86.5 | (83.8-88.8) | 82.3 | (79.2-84.9) | 80.3 | (77.0-83.2) |
| AYAe (15-39) | 2,050 | 93.5 | (92.3-94.5) | 86.7 | (85.0-88.1) | 69.5 | (67.2-71.7) | 51.7 | (48.8-54.5) | |
| Adults (40+) | 3,815 | 56.8 | (55.2-58.4) | 42.7 | (41.1-44.4) | 28.9 | (27.3-30.6) | 20.3 | (18.5-22.0) | |
| Anaplastic astrocytoma | Childrend (0-14) | 229 | 60.3 | (53.6-66.4) | 39.3 | (32.8-45.8) | 28.5 | (22.4-34.9) | 23.5 | (17.6-29.9) |
| AYAe (15-39) | 1,107 | 88.5 | (86.4-90.3) | 74.4 | (71.5-77.0) | 51.3 | (47.8-54.7) | 37.6 | (33.7-41.5) | |
| Adults (40+) | 2,765 | 51.7 | (49.7-53.6) | 32.2 | (30.4-34.1) | 18.5 | (16.8-20.2) | 12.1 | (10.5-13.9) | |
| Glioblastoma | Childrend (0-14) | 297 | 50.5 | (44.5-56.1) | 28.9 | (23.5-34.4) | 20.0 | (15.2-25.3) | 14.8 | (10.2-20.3) |
| AYAe (15-39) | 1,901 | 71.8 | (69.6-73.8) | 44.8 | (42.4-47.1) | 22.5 | (20.4-24.7) | 13.7 | (11.7-15.9) | |
| Adults (40+) | 31,006 | 34.9 | (34.4-35.5) | 13.3 | (12.8-13.7) | 3.7 | (3.5-4.0) | 1.7 | (1.4-1.9) | |
| Oligodendroglioma | Childrend (0-14) | 157 | 95.5 | (90.7-97.8) | 94.8 | (89.8-97.4) | 92.0 | (86.2-95.4) | 90.2 | (83.7-94.2) |
| AYAe (15-39) | 1,476 | 98.4 | (97.6-99.0) | 96.1 | (94.9-97.0) | 87.6 | (85.5-89.3) | 71.0 | (67.8-73.9) | |
| Adults (40+) | 1,969 | 90.3 | (88.8-91.6) | 84.1 | (82.2-85.7) | 72.7 | (70.3-74.9) | 56.0 | (52.8-59.0) | |
| Anaplastic oligodendroglioma | Childrend (0-14) | – | – | – | – | – | – | – | – | – |
| AYAe (15-39) | 403 | 93.4 | (90.4-95.5) | 83.6 | (79.3-87.0) | 67.2 | (61.8-72.1) | 50.0 | (43.5-56.2) | |
| Adults (40+) | 1,023 | 76.7 | (73.9-79.3) | 63.1 | (59.9-66.2) | 46.9 | (43.4-50.3) | 34.4 | (30.5-38.3) | |
| Ependymal tumors | Childrend (0-14) | 695 | 93.6 | (91.5-95.2) | 86.5 | (83.6-88.9) | 72.9 | (69.1-76.4) | 64.4 | (59.8-68.6) |
| AYAe (15-39) | 842 | 96.6 | (95.1-97.7) | 94.0 | (92.0-95.5) | 89.8 | (87.2-91.9) | 86.2 | (82.8-88.9) | |
| Adults (40+) | 1,392 | 92.3 | (90.6-93.7) | 88.8 | (86.7-90.5) | 84.9 | (82.4-87.2) | 82.6 | (79.3-85.5) | |
| Oligoastrocytic tumors | Childrend (0-14) | 83 | 95.1 | (87.3-98.2) | 87.2 | (77.3-92.9) | 80.7 | (69.3-88.2) | 75.6 | (62.0-84.9) |
| AYAe (15-39) | 928 | 96.8 | (95.4-97.8) | 90.9 | (88.7-92.7) | 74.4 | (71.0-77.5) | 57.1 | (52.5-61.5) | |
| Adults (40+) | 1,119 | 79.5 | (76.9-81.8) | 66.5 | (63.4-69.4) | 50.2 | (46.8-53.6) | 37.6 | (33.4-41.7) | |
| Glioma malignant, NOS | Childrend (0-14) | 1,567 | 75.5 | (73.2-77.6) | 63.0 | (60.5-65.5) | 59.7 | (57.0-62.2) | 58.1 | (55.3-60.7) |
| AYAe (15-39) | 872 | 89.2 | (86.9-91.1) | 81.8 | (78.9-84.3) | 69.4 | (65.7-72.7) | 56.8 | (52.2-61.1) | |
| Adults (40+) | 2,278 | 44.6 | (42.4-46.7) | 34.1 | (32.0-36.2) | 27.5 | (25.4-29.6) | 23.2 | (21.0-25.6) | |
| Neuronal and mixed neuronal-glial tumors | Childrend (0-14) | – | – | – | – | – | – | – | – | – |
| AYAe (15-39) | 132 | 96.2 | (91.0-98.5) | 91.4 | (84.8-95.2) | 78.9 | (69.8-85.5) | 66.6 | (53.2-77.0) | |
| Adults (40+) | 370 | 87.7 | (83.6-90.9) | 79.7 | (74.7-83.9) | 72.4 | (66.3-77.5) | 56.3 | (47.8-64.0) | |
| Embryonal tumors | Childrend (0-14) | 2,021 | 79.9 | (78.1-81.6) | 70.0 | (67.8-72.0) | 61.6 | (59.3-63.9) | 55.8 | (53.3-58.3) |
| AYAe (15-39) | 773 | 88.6 | (86.1-90.7) | 79.7 | (76.6-82.5) | 64.9 | (61.0-68.5) | 55.7 | (51.3-59.9) | |
| Adults (40+) | 246 | 72.9 | (66.6-78.2) | 58.0 | (51.1-64.3) | 45.4 | (38.1-52.4) | 33.5 | (25.9-41.4) | |
| Meningioma | Childrend (0-14) | – | – | – | – | – | – | – | – | – |
| AYAe (15-39) | 103 | 98.1 | (92.1-99.6) | 98.1 | (92.1-99.6) | 89.4 | (80.4-94.4) | 85.6 | (75.4-91.8) | |
| Adults (40+) | 1,126 | 81.6 | (78.9-83.9) | 73.8 | (70.7-76.5) | 62.8 | (59.2-66.3) | 54.7 | (50.1-59.0) | |
| Lymphoma | Childrend (0-14) | – | – | – | – | – | – | – | – | – |
| AYAe (15-39) | 824 | 42.5 | (39.0-45.9) | 36.5 | (33.2-39.9) | 31.5 | (28.2-34.8) | 26.0 | (22.6-29.6) | |
| Adults (40+) | 4,306 | 49.3 | (47.7-50.8) | 40.2 | (38.6-41.7) | 28.9 | (27.4-30.5) | 20.7 | (18.9-22.5) | |
| TOTAL: All Brain and Other Nervous Systemg | Childrend (0-14) | 9,134 | 85.6 | (84.8-86.3) | 78.4 | (77.5-79.2) | 72.7 | (71.7-73.6) | 69.0 | (67.9-70.1) |
| AYAe (15-39) | 13,701 | 87.3 | (86.7-87.8) | 78.5 | (77.7-79.2) | 65.4 | (64.5-66.3) | 54.2 | (53.1-55.2) | |
| Adults (40+) | 54,817 | 46.0 | (45.6-46.5) | 29.5 | (29.0-29.9) | 19.7 | (19.3-20.1) | 15.0 | (14.6-15.5) | |
aThe cohort analysis of survival rates was utilized for calculating the survival estimates presented in this table. Long-term cohort-based survival estimates reflect the survival experience of individuals diagnosed over the time period, and they may not necessarily reflect the long-term survival outlook of newly diagnosed cases.
bRates are an estimate of the percentage of patients alive at one, two, five, and ten year, respectively. Rates were not presented for categories with 50 or less cases and were suppressed for rates where less than 16 cases were surviving within a category.
cEstimated by CBTRUS using Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER 18 Registries Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2014 Sub (1973-2012 varying) - Linked To County Attributes - Total U.S., 1969-2013 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2015, based on the November 2014 submission.
dTotal number of case that occurred within the SEER registries between 1995 and 2012
eChildren as defined by the National Cancer Institute, see: http://www.cancer.gov/researchandfunding/snapshots/pediatric.
fAdolescents and Young Adults (AYA), as defined by the National Cancer Institute, see: http://www.cancer.gov/researchandfunding/snapshots/adolescent-young-adult.
gIncludes histologies not listed in this table.
Abbreviation: SEER, Survival, Epidemiology and End Results; CI, confidence interval; NOS, not otherwise specified.