Table 1.

Effect of G6–31 (10 mg/kg) on microvascular density in K-ras^LA1 lung tumors, assessed from vWFimmunostaining. Quantification of the microvascular density (MVD) of small (< 10 μm) and large (> 10 μm) vascular structures (n = 30 mice per group; control and G6–31 10 mg/kg; *P< 0.05 Mann-Whitney test)

	vWF% (± SEM)
	I.P. G6–31 / Placebo	Aerosol G6–31 / Placebo
Small vessel (< 10 μm)	+ 9.85 (± 20.05)	− 44.21 (± 7.67)
	P = 0.96	P = 0.018
Large vessel (> 10 μm)	− 43.10 (± 12.09)	− 11.50 (± 14.69)
	P = 0.0096	P = 0.27