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. Author manuscript; available in PMC: 2015 Oct 28.
Published in final edited form as: Liver Transpl. 2014 Jan 2;20(2):218–227. doi: 10.1002/lt.23788

Figure 1.

Figure 1

Patient 1 was a 56-year-old female with a gynecological history significant for 1 still birth and with a MELD score of 12 who underwent primary LT for AIH with a 37-year-old male donor after 12.2 hours of cold ischemia in 1990. She had (A) saturation of single-antigen beads of numerous DSAs at a 1:81 dilution against class I before transplantation, (B) 7 distinct DSAs (MFIs reported at a 1:3 dilution) in all, and (C) a clinical course characterized by early postoperative platelet consumption and recurrent rejection. (D) The postreperfusion biopsy showed endothelial reactivity and diffuse C4d positivity (top panels), and this was followed by evidence of combined AMR and ACR on day 16 characterized by diffuse microvascular endothelial cell injury (bottom panels).