Table 3.

Median survival time of F98 glioma bearing Fischer rats

Treatmenta	MSTd (days)	MeSTc (days)	Range (days)	P valuef
5% Dextrose	22.9 ± 2.1	23.5	19–25
5% Dextrose + 15 Gyb	31.8 ± 5.2	30.0	26–35	P=0.0002
7.5 μg Cisplatinc	36.1 ± 6.6	35.5	25–46	P<0.0001
7.5 μg Cisplatin + 15 Gy	39.3 ± 4.5	39.0	32–45	P=0.0002
7.5 μgLipoplatin™	27.0 ± 2.0	26.5	25–31	P=0.0004
25 μg Carboplatin	40.9 ± 6.0	38.5	31–47	P<0.0001
25 μg Carboplatin + 15 Gy	53.1 ± 9.6	54.0	39–65	P<0.0001

^aInjection volume = 10 μL.

^bRadiotherapy was delivered 24 h after chemotherapy.

^cDrugs were tested at their respective MTD.

^dMean Survival Time

^eMedian Survival Time

^fCompared to 5% Dextrose