Table 4.
Survival time and acute toxicity of F98 glioma bearing Fischer rats treated with radiotherapy at 4 h or 24 h after CED of platinum-based drugs.
dextrose + GK 4 h | dextrose + GK 24 h | carboplatin + GK 4 h | carboplatin + GK 24 h | |
---|---|---|---|---|
MeST (days) | 30.5 | 30.0 | 54.5 | 54.0 |
| ||||
Number of rats tested | 8 | 8 | 11 | 8 |
Number of rats manifesting symptoms of toxicity | 0 | 0 | 4 | 3 |
Number of rats euthanized due to intolerable toxicity | 0 | 0 | 3 | 0 |