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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Invest New Drugs. 2015 Mar 18;33(3):555–563. doi: 10.1007/s10637-015-0228-4

Table 4.

Survival time and acute toxicity of F98 glioma bearing Fischer rats treated with radiotherapy at 4 h or 24 h after CED of platinum-based drugs.

dextrose + GK 4 h dextrose + GK 24 h carboplatin + GK 4 h carboplatin + GK 24 h
MeST (days) 30.5 30.0 54.5 54.0

Number of rats tested 8 8 11 8
Number of rats manifesting symptoms of toxicity 0 0 4 3
Number of rats euthanized due to intolerable toxicity 0 0 3 0
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