Table 1.
Characteristics of articles on inflammatory/protein mediators in intra-abdominal sepsis or injury
| Characteristics | Number (%) of 182 articles |
|---|---|
| Type of article | |
| Clinical study | 103 (57 %) |
| Biomarker or diagnosis study | 63 (35 %) |
| Intervention study | 9 (5 %) |
| Mechanistic or kinetic study | 31 (17 %) |
| Study design | |
| Randomized controlled trials | 4 |
| Nonrandomized controlled trials | 5 |
| Cohort study | 36 |
| Case-control study | 29 |
| Case series | 29 |
| Abdominal sepsis | 64 |
| Abdominal injury or ischemia-reperfusion | 27 |
| Mixed sepsis and injury | 12 |
| Preclinical study | 79 (43 %) |
| Intervention study | 32 (17 %) |
| Mechanistic study | 47 (26 %) |
| Study design | |
| Rodent model | 69 |
| Porcine model | 7 |
| Canine model | 1 |
| Rabbit model | 1 |
| Baboon model | 1 |
| Injury or ischemia-reperfusion | 26 |
| Abdominal sepsis | 44 |
| Mixed injury and sepsis | 9 |
| Year of publication | |
| 1985–1994 | 14 (8 %) |
| 1995–2004 | 65 (35 %) |
| 2005–2014 | 103 (57 %) |
| Country of origin | |
| European countries | 80 (44 %) |
| United States of America | 44 (24 % |
| Other countries | 58 (32 %) |