Table 1.
Clinicopathological parameters and survival analysis in 102 primary UPS tumors
P | ||||||
---|---|---|---|---|---|---|
Variable | Group | No. | (%) | Analyzed groups | Overall survival | Event-free survival |
Sex | Male | 45 | 44.1 | 0.3077 | 0.1815 | |
Female | 57 | 55.9 | ||||
Age (17 ~ 93, mean: 62) | <62 | 53 | 52 | 0.3714 | 0.1518 | |
≧62 | 49 | 48 | ||||
Size | <5 cm | 35 | 34.3 | 0.0058a | 0.0008a | |
≧5 cm | 56 | 54.9 | ||||
N/A | 11 | 10.8 | ||||
Location | Superficial | 42 | 41.2 | 0.0154a | 0.0193a | |
Deep | 54 | 52.9 | ||||
NA | 6 | 5.9 | ||||
Chemotherapy | Yes | 20 | 19.6 | 0.5761 | 0.9270 | |
No | 30 | 29.4 | ||||
NA | 52 | 51.0 | ||||
Surgical margin | Positive | 18 | 17.6 | 0.3069 | 0.9937 | |
Negative | 45 | 44.1 | ||||
NA | 39 | 38.3 | ||||
Metastasis | + | 28 | 27.5 | <0.0001a | <0.0001a | |
- | 74 | 72.5 | ||||
Reccurence | + | 16 | 15.7 | 0.9212 | <0.0001a | |
- | 86 | 84.3 | ||||
Necrosis | 0, score 0 | 58 | 56.9 | Score 0 vs others | 0.0011a | 0.0101a |
<50 %, score 1 | 31 | 30.4 | Score 1 vs score 2 | 0.464 | 0.6221 | |
≧50 %, score 2 | 13 | 12.7 | Score 2 vs others | 0.0344a | 0.2112 | |
Mitosis | 0–9/10 HPF, score 1 | 53 | 52 | Score 1 vs others | 0.0003a | 0.0005a |
10–19/10 HPF, score 2 | 28 | 27.4 | Score 2 vs score 3 | 0.0291a | 0.4872 | |
20≧/10 HPF, score 3 | 21 | 20.6 | Score 3 vs others | <0.0001a | 0.0077a | |
MIB-1 LI | <10 % | 20 | 26.7 | 0.0569 | 0.0533 | |
≧10 % | 50 | 66.7 | ||||
NA | 5 | 6.6 | ||||
FNCLCC | 2 | 64 | 62.7 | <0.0001a | 00002a | |
3 | 38 | 37.3 | ||||
AJCC 7th ed | II | 59 | 57.8 | Stage II vs others | <0.0001a | <0.0001a |
III | 15 | 14.7 | Stage III vs IV | 0.0614 | <0.0001a | |
IV | 28 | 27.5 |
AJCC American Joint Committee on Cancer, FNCLCC French Federation of Cancer Centers, HPF high-power fields, LI labeling index, N/A not available, No. number of patients. The Fisher exact test or the log-rank test was used if not indicated otherwise
aStatistically significant