Table 3.
Target Monitoring Times Following Once Daily Dexamethasone in 5 patients with Classic CAH
Once Daily Dose | ||
---|---|---|
| ||
TminAC (h)1 | TmaxAC (h)1 | |
ACTH | 5.8 (1.9) | 20.2 (4.4) |
17OHP | 9.4 (1.8) | 17.4 (6.5) |
Androstenedione | 9.0 (4.8) | 15.4 (8.4) |
Androsterone | 6.2 (2.2) | 17.4 (8.7) |
DHEA | 3.4 (2.9) | 21.4 (3.6) |
Testosterone | 3.8 (2.4) | 20.6 (7.6) |
Progesterone | 6.2 (1.9) | 11.8 (7.6) |
Dexamethasone (Dose Range - HC equiv: 9.6 – 21.3mg/m2/day)
Mean (SD)
TminAC, the number of hours from dose administration to minimal adrenocortical (AC) hormone level; TmaxAC, the number of hours from dose administration to the maximal AC hormone level