Fig 6. TrxG complex proteins are expressed in adult islet cells and are largely non-responsive to IFNγ, Il-1β, and TNFα exposure.

(A) Expression level (FPKM) of the genes for the primary proteins in the TrxG complexes in untreated and IFNγ, Il-1β, and TNFα (cytokine) treated islets. (B) qPCR validation of the unaltered expression of the genes for the primary proteins in the TrxG complexes in IFNγ, Il-1β, and TNFα (cytokine) treated islets as compared to untreated islets. (C) Immunohistochemical co-staining of selected TrxG proteins (green) and insulin (red) in adult pancreas sections. Topro staining (blue) is shown in the merged image to identify nuclei.