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Micromass is an adaptable culture method. Skeletal progenitor cells are typically isolated from the embryonic limb buds (indicated by the red box), cultured in micromass, and analyzed by various standard laboratory techniques. The classic micromass can be supplemented with a range of genetic, molecular, and bioengineering tools to create an interdisciplinary model system to study early skeletal development in vitro. Color images available online at www.liebertpub.com/teb
