Table 1.
Patient characteristics, by quartile of baseline physical function score
| PF Score Quartile | ||||||
|---|---|---|---|---|---|---|
| Total (N=19242) | Q1 (Highest; n=4253) | Q2 (n=5287) | Q3 (n=4492) | Q4 (Lowest; n=5210) | p-value | |
| PF Score | 50 (35,80) | 90 (85,95) | 70 (65,75) | 50 (45,50) | 20 (10,30) | <0.001 |
| Range | 0-100 | 85-100 | 60-80 | 40-55 | 0-35 | |
| Age (y) | 51 (41,59) | 46 (36,56) | 50 (40,59) | 52 (42,60) | 54 (45,61) | <0.001 |
| Follow Up Time (y) | 5.8 (4.2,7.5) | 6.3 (4.9,7.9) | 6.0 (4.4,7.6) | 5.7 (4.0,7.4) | 5.3 (3.0,7.0) | <0.001 |
| Age category | <0.001 | |||||
| <35 y | 2692 (14) | 966 (23) | 796 (15) | 508 (11) | 422 (8) | |
| 35-<45 y | 3671 (19) | 1001 (24) | 1020 (19) | 857 (19) | 793 (15) | |
| 45-<55 y | 5391 (28) | 1109 (26) | 1491 (28) | 1299 (29) | 1492 (29) | |
| 55-<65 y | 5165 (27) | 797 (19) | 1361 (26) | 1242 (28) | 1765 (34) | |
| ≥65 y | 2323 (12) | 380 (9) | 619 (12) | 586 (13) | 738 (14) | |
| Sex | ||||||
| Female | 7732 (40) | 1344 (32) | 2030 (38) | 1902 (42) | 2456 (47) | <0.001 |
| Male | 11510 (60) | 2909 (68) | 3257 (62) | 2590 (58) | 2754 (53) | |
| Race | ||||||
| White | 7676 (40) | 1689 (40) | 2120 (40) | 1716 (38) | 2151 (41) | <0.001 |
| Black | 6939 (36) | 1569 (37) | 1968 (37) | 1688 (38) | 1714 (33) | |
| Hispanic | 3531 (18) | 751 (17) | 892 (17) | 805 (18) | 1083 (21) | |
| Asian | 694 (4) | 144 (3) | 192 (4) | 179 (4) | 179 (3) | |
| Other | 402 (2) | 98 (2) | 116 (2) | 105 (2) | 83 (2) | |
| Cause of ESRD | <0.001 | |||||
| Diabetes | 6170 (32) | 922 (22) | 1518 (29) | 1525 (34) | 2205 (42) | |
| Hypertension | 4719 (25) | 1164 (27) | 1347 (26) | 1118 (25) | 1090 (21) | |
| Glomerulonephritis | 3093 (16) | 896 (21) | 921 (17) | 637 (14) | 639 (12) | |
| Polycystic Kidney | 1039 (5) | 288 (7) | 318 (6) | 213 (5) | 220 (4) | |
| Congenital/Reflux | 225 (1) | 68 (2) | 62 (1) | 50 (1) | 45 (1) | |
| Other or Unknown | 3996 (21) | 915 (22) | 1121 (21) | 949 (21) | 1011 (19) | |
| Diabetes | <0.001 | |||||
| No Diabetes | 11357 (59) | 3077 (72) | 3320 (63) | 2560 (57) | 2400 (46) | |
| Diabetes | 7885 (41) | 1176 (28) | 1967 (37) | 1932 (43) | 2810 (54) | |
| Median BMI | <0.001 | |||||
| Underweight | 490 (3) | 88 (2) | 152 (3) | 109 (2) | 141 (3) | |
| Healthy Weight | 6263 (33) | 1551 (37) | 1760 (33) | 1402 (31) | 1550 (30) | |
| Overweight | 6222 (33) | 1458 (35) | 1689 (32) | 1447 (32) | 1628 (31) | |
| Obese | 3874 (20) | 726 (17) | 1060 (20) | 935 (21) | 1153 (22) | |
| Severely Obese | 2295 (12) | 408 (10) | 601 (11) | 575 (13) | 711 (14) | |
| Peripheral vascular disease | ||||||
| Disease | 1087 (6) | 137 (3) | 235 (4) | 258 (6) | 457 (9) | |
| No Disease | 16830 (88) | 3789 (89) | 4723 (89) | 3917 (87) | 4401 (85) | |
| Unknown/Missing | 1312 (7) | 323 (8) | 327 (6) | 315 (7) | 347 (7) | |
| Prior Kidney Tx | 0.06 | |||||
| No Prior Tx | 17015 (88) | 3739 (88) | 4672 (88) | 3946 (88) | 4658 (89) | |
| Prior Tx | 2227 (12) | 514 (12) | 615 (12) | 546 (12) | 552 (11) | |
| Blood type | 0.9 | |||||
| AB | 627 (3) | 131 (3) | 182 (3) | 150 (3) | 164 (3) | |
| A | 5895 (31) | 1313 (31) | 1630 (31) | 1341 (30) | 1611 (31) | |
| B | 2915 (15) | 649 (15) | 804 (15) | 702 (16) | 760 (15) | |
| O | 9805 (51) | 2160 (51) | 267 (51) | 2299 (51) | 2675 (51) | |
| Insurance Type | <0.001 | |||||
| Private | 6556 (34) | 1736 (41) | 1872 (35) | 1410 (31) | 1538 (30) | |
| Medicare | 10982 (57) | 2165 (51) | 2986 (57) | 2646 (59) | 3185 (61) | |
| Other | 1697 (9) | 350 (8) | 428 (8) | 435 (10) | 484 (9) | |
| Time since dialysis initiation | <0.001 | |||||
| <1 y | 5887 (31) | 1437 (34) | 1629 (31) | 1359 (30) | 1462 (28) | |
| 1-3 y | 8344 (43) | 1779 (42) | 2323 (44) | 1893 (42) | 2349 (45) | |
| >3 y | 4997 (26) | 1033 (24) | 1333 (25) | 1238 (28) | 1393 (27) | |
| Dialysis modality | <0.001 | |||||
| Hemodialysis | 17231 (90) | 3773 (89) | 4690 (89) | 4011 (89) | 4757 (91) | |
| Peritoneal dialysis | 2011 (10) | 480 (11) | 597 (11) | 481 (11) | 453 (9) | |
| Wait-listed before UNOS policy change* | 0.3 | |||||
| Yes | 4566 (39) | 1639 (39) | 2056 (39) | 1771 (39) | 2100 (40) | |
| No | 11676 (61) | 2614 (62) | 3231 (61) | 2721 (61) | 3110 (60) | |
| Geographic quartile of time to kidney Tx* (%) | 0.02 | |||||
| Shortest | 2496 (13) | 561 (13) | 711 (14) | 580 (13) | 644 (12) | |
| Near Shortest | 3388 (18) | 788 (19) | 960 (18) | 790 (18) | 850 (16) | |
| Near Longest | 7043 (37) | 1568 (37) | 1930 (37) | 1614 (36) | 1931 (37) | |
| Longest | 6304 (33) | 1333 (31) | 1685 (32) | 1504 (34) | 1782 (34) | |
| Any Kidney Tx Outcome# | 11,050 (57) | 2886 (68) | 3247 (61) | 2516 (56) | 2401 (46) | <0.001 |
| Deceased Donor Tx | 9207 (90) | 2351 (87) | 2732 (90) | 2108 (91) | 2016 (93) | <0.001 |
| Living Donor Tx | 1843 (10) | 535 (13) | 515 (10) | 408 (9) | 385 (7) | <0.001 |
Note: Missing data was <1% for all variables except peripheral vascular disease. Values for categorical variables are given as number (percentage); for continuous variables, as median [interquartile range], except as noted.
BMI, body mass index; ESRD, end-stage renal disease; PF, physical function; Tx, transplant or transplantation; UNOS, United Network for Organ Sharing
*
November 1, 2003 allowing priority to accrue during inactive time.
*
Calculated among all kidney Tx candidates in each donor service area (geographic region defined by Organ Procurement and Transplantation Network that is strongly associated with organ availability through allocation)
#
Living or deceased donor.