Table 2.
Multivariable Cox regression analysis of receipt of kidney transplant
| Physical Function | Unadjusted* (n=19,242) | Adjusted* (n=17,821) | Adjusted** (n=17,821) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | p-value | Adjusted HR (95% CI) | p-value | Adjusted HR (95% CI) | p-value | ||||
| Q1: Highest | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | ||||||
| Q2 | 0.89 (0.85-0.94) | <0.001 | 0.95 | 0.90, 1.00 | 0.04 | 0.94 | 0.89, 0.99 | 0.01 | |
| Q3 | 0.81 | 0.77, 0.86 | <0.001 | 0.91 | 0.86, 0.96 | 0.001 | 0.81 | 0.76, 0.86 | <0.001 |
| Q4: Lowest | 0.66 | 0.63, 0.70 | <0.001 | 0.74 | 0.70, 0.79 | <0.001 | 0.64 | 0.61, 0.68 | <0.001 |
Note: Model adjusted for age, sex, race, primary insurance type, diabetes, prior kidney transplant, peripheral vascular disease, glomerulonephritis as cause of ESRD, polycystic disease as cause of ESRD, congenital or reflux disease as cause of ESRD, hypertension as cause of ESRD, blood type, body mass index, time since dialysis initiation, dialysis modality and geographic quartile of time to transplantation defined at level of the donor service area where the candidate was listed.
CI, confidence interval; ESRD, end-stage renal disease; HR, hazard ratio; Q, quartile
Physical function categories defined at baseline without time-updates.
Time-updated physical function categories.