Table 3.

Multivariable Cox regression analysis of time to first inactivation on kidney transplant waiting list

Physical Function	Unadjusted* (n=18,726)			Adjusted* (n=17,331)			Adjusted** (n=17,331)
	HR (95% CI)		p	Adjusted HR (95% CI)		p	Adjusted HR (95% CI)		p
Q1: Highest	1.00 (reference)			1.00 (reference)			1.00 (reference)
Q2	1.10 (1.04-1.17)		0.002	1.11	1.04, 1.19	0.003	1.12	1.05, 1.20	0.001
Q3	1.15	1.08, 1.23	<0.001	1.16	1.08, 1.24	<0.001	1.22	1.13, 1.31	<0.001
Q4: Lowest	1.29	1.22, 1.38	<0.001	1.27	1.18, 1.36	<0.001	1.30	1.21, 1.39	<0.001

Note” Model adjusted for age, sex, race, primary insurance type, diabetes, prior kidney transplant, peripheral vascular disease, glomerulonephritis as cause of ESRD, polycystic disease as cause of ESRD, congenital or reflux Disease as cause of ESRD, hypertension as cause of ESRD, blood type, body mass index, time since dialysis initiation, dialysis modality, geographic quartile of time to transplantation defined at level of donor service area where candidate was listed, and era (defined as before or after United Network for Organ Sharing policy change allowing priority to accrue during inactive time)

CI, confidence interval; ESRD, end-stage renal disease; HR, hazard ratio; Q, quartile

^*Physical function categories defined at baseline without time-updates

^**Time-updated physical function categories