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. Author manuscript; available in PMC: 2016 Dec 14.
Published in final edited form as: Phys Chem Chem Phys. 2015 Dec 14;17(46):30867–30875. doi: 10.1039/c5cp01246e

Scheme 1.

Scheme 1

Proposed chemical mechanism for TSase Catalyzed Reaction (reproduced from ref.13 with permission from ACS). The proton being abstracted in step 4 is shown in green.