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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Addict Biol. 2015 Apr 27;21(3):613–633. doi: 10.1111/adb.12252

Figure 2.

Figure 2

Summary of the effects of unpredictable chronic mild stress (UCMS) upon alcohol intake and preference. During the first 24 h of alcohol availability, mice subjected to our UCMS procedures consumed a marginally higher total volume of fluid (A) and a significantly larger volume of water (B), compared to mice subjected to our control procedures (Control). (C) During this time, group differences were not observed in the dose-response function for alcohol preference, however (D) UCMS mice consumed a greater amount of both 10% and 20% alcohol, relative to controls. When averaged across the 5 days of alcohol availability, there was no group difference in the total volume consumed (E) or in water intake (F). In contrast, UCMS mice exhibited a greater average preference for (G), and intake of (H), 20% alcohol. n=12/group. +p<0.05 vs. Control (t-tests).