Table 2.

Summary of the health outcomes of the mice following UCMS procedures. The average change in body weight of UCMS and control Swiss-Webster (SW), Homer2 wild-type (WT) and knock-out (KO) mice from Day 1 to 11 of UCMS procedures is presented, in addition to a summary of the total coat condition score of Homer2 WT and KO mice. Swiss-Webster mice did not receive any score for coat condition and thus, their data are not presented herein. Data were analyzed by either t-tests or ANOVAs and the results of these analyses are presented below. Sample sizes are indicated in parentheses.

Study	Control	UCMS	Statistic
Change in Body Weight (g)
SW Cross-sensitization	1.50 ± 0.22 (24)	1.18 ± 0.21 (24)	t(46)=1.05, p=0.30
SW Drinking	0.31 ± 1.03 (12)	−2.17 ± 0.57 (12)	t(22)=2.11, p=0.05
SW Intoxication	1.24 ± 0.32 (10)	0.85 ± 0.47 (10)	t(18)=0.69, p=0.50
Homer2 WT	0.88 ± 0.35 (13)	−0.35 ± 0.31 (14)	UCMS effect: F(1,54)=8.80, p=0.005 Genotype effect: p=0.51 UCMS X Genotype: p=0.57
Homer2 KO	0.45 ± 0.29 (12)	−0.38 ± 0.39 (16)
Total Coat Score
Homer2 WT	0.12 ± 0.06 (13)	0.00 ± 0.00 (14)	UCMS effect: F(1,54)=0.99, p=0.33 Genotype effect: p=0.23 UCMS X Genotype: p=0.20
Homer2 KO	0.08 ± 0.05 (12)	0.94 ± 0.63 (16)