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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Curr Opin Organ Transplant. 2015 Oct;20(5):506–514. doi: 10.1097/MOT.0000000000000232

Table 3.

Clinical risk factors for PGD

Category Risk factors for Primary Graft Dysfunction
Donor inherent variables Age>45 or <21yo
African American race
Female sex
Smoke exposure
Donor acquired variables Prolonged mechanical ventilation
Aspiration
Head trauma
Hemodynamic instability after brain death
Recipient variables Female gender
Body mass index>25
Pulmonary arterial hypertension
Pulmonary hypertension secondary to parenchymal lung disease
Idiopathic pulmonary fibrosis
Sarcoidosis
Elevated pulmonary arterial pressure at time of surgery
Operative variables Single lung transplantation
Prolonged ischemic time
Use of cardiopulmonary bypass
Packed red blood transfusion > 1L
High reperfusion FiO2 > 0.4
Use of Euro-Collins preservation solution

Adapted from References (6, 11, 12, 14, 32, 79-83, 87, 89, 90, 93-100)