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. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611

Fig 6. Vascular development in vhl hu2117 mutants is unaffected by the klf2a sh317 mutation.

Fig 6

Wildtype embryos exhibit angiogenesis typical for this developmental stage– 3dpf (left figure, white arrow). Homozygous vhl hu2117 embryos show enlargement of vessels (ISVs and DLAV) with increased tortuosity and looping of the DLAV (middle figure, right arrow). The same vascular phenotype was be observed in vhl hu2117 embryos in a homozygous klf2a sh317 background (right figure, red arrow). Confocal images of Tg(fli1:eGFP) zebrafish embryos at 3dpf.. Scale bar = 70μm.