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Pharmacokinetic parameters of loureirin B after oral administration of longxuejie (16 g/kg) to rats (n = 6, mean ± standard deviation.
| Parameters | Values |
|---|---|
| Kel (/h) | 0.365 ± 0.06 |
| t1/2 (h) | 1.94 ± 0.27 |
| T max (h) | 0.81 ± 0.11 |
| Cmax (μg/L) | 7.99 ± 1.2 |
| AUC0–T (μg h/L) | 22.2 ± 1.9 |
| AUC0–∞ (μg h/L) | 22.6 ± 1.8 |
| Cl (l/h/kg) | 978.2 ± 117.3 |
| Vc (l/kg) | 2768.6 ± 751.5. |
AUC = area under the concentration-time curve; Cl = clearance; Cmax = peak plasma concentration; Tmax = time of peak plasma concentration.
