Table 18.
The main pharmacokinetic parameters of quercetin in rats.
| Parameter | GBE | GBP | GBS |
|---|---|---|---|
| Ke (1/h) | 0.0541 | 0.1909 | 0.1124 |
| Ka (1/h) | 0.6376 | 1.4162 | 1.3592 |
| Tmax (h) | 1.21 | 1.02 | 0.63 |
| Cmax (ng/mL) | 179.21 | 724.89 | 419.02 |
| AUC (0∼T) (ng/h/mL) | 1368.26 | 3321.05 | 2841.63 |
| MRT (0∼T) (h) | 5.4791 | 4.1442 | 4.6633 |
| CL/F(s) (ng/h/(ng/mL)) | 0.0015 | 0.0033 | 0.0038 |
AUC = area under the concentration-time curve; Cmax = peak plasma concentration; GBE = Ginkgo biloba extract; GBP = G. biloba extract phospholipid complexes; GBS = G. biloba extract solid dispersions; MRT = mean residence time; Tmax = time of peak plasma concentration; CL/F = Apparent clearance; Ke = elimination rate constant.