Table 21.
Pharmacokinetic parameters of HEDT-Glu Following after intravenous administration 13.2 mg·kg−1 HEDT-Glu in rats (n = 6).
Parameters | Values |
---|---|
AUC | 16.04 ± 3.19 μ g·h·mL−1. |
Elimination half-life at the α phases (t1/2,a) | 0.06 ± 0.01 h |
Elimination half-life at the β phase (t1/2,b) phases | 1.27 ± 0.31 h |
Ke | 9.78 ± 1.61 h−1 |
CL | 0.85 ± 0.17 l·kg−1·h−1. |
AUC = area under the concentration-time curve; CL = clearance; Ke = elimination rate constant.