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Pharmacokinetic parameters of prim-O-glucosylcimifugin and 4-O-d-glucosyl-5-O methylvisamminol in rats after oral administration of Fangfeng extract.
| Parameters | Compounds |
|
|---|---|---|
| Prim-O-glucosylcimifugin | 4-O-d-glucosyl-5-O-methylvisamminol | |
| T1/2 (h) | 1.31 | 1.96 |
| Cmax (ng/mL) | 39.92 | 41.53 |
| Tmax (h) | 0.54 | 0.56 |
| AUC(0–t) (ng/mL h) | 66.77 | 65.65 |
| AUC(0–∞) (ng/mL h) | 75.63 | 73.05 |
AUC = area under the concentration-time curve; Cmax = peak plasma concentration; Tmax = time of peak plasma concentration.
