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. 2015 Jan 28;5(4):207–227. doi: 10.1016/j.jtcme.2014.11.041

Table 51.

Pharmacokinetic parameters of acteoside in rats after 10 mg/kg administration.

Parameters Estimated
A (μg/mL) 71.9 ± 30.9
B (μg/mL) 2.9 ± 0.5
α (L/min) 0.14 ± 0.03
β (L/min) 0.02 ± 0.004
t1/2α (min) 5.0 ± 1.2
t1/2β (min) 28.5 ± 4.7
AUC (min μg/mL) 592.3 ± 124.7
Vss (mL/kg) 277.7 ± 185.8
Cl (mL/min/kg) 17.7 ± 4.5

Data expressed as mean ± standard deviation (n = 6); t1/2, α: distribution half-life; t1/2, β: elimination half-life.

AUC = area under the concentration-time curve; Cl = clearance; Vss = volume of distribution at steady state.