Table 1.
Demographics of patients who had evaluation of the chest and abdomen for fungus with computed tomography before and within 100 days post-HSCT
| Characteristic | CAF Pre-HSCT (n = 66) |
CAF Day 0–100 post-HSCT (n = 37) |
|---|---|---|
| Age (years) | ||
| Mean (SD) | 9.1 (6.4) | 9.6 (6.1) |
| Median (Range) | 8.8 (0.2–20.4) | 9.1 (0.6–20.4) |
| Male sex | 36 (55) | 18 (49) |
| Diagnosis heme malignancy | 58 (87) | 32 (87) |
| Remission | 28 (42) | 20 (54) |
| Total body irradiation | 19 (29) | 13 (35) |
| Product Type | ||
| Bone marrow | 37 (56) | 18 (48) |
| Peripheral blood | 24 (36) | 15 (41) |
| Cord | 5 (8) | 4 (11) |
| History IFI | 7 (11) | 4 (11) |
| Positive galactomannan | 0 (0) | 3 (8) |
| ANC (cells/μL) | ||
| Mean (SD) | 1027 (1276) | 892 (1233) |
| Median (range) | 500 (0– 4400) | 500 (0–4400) |
| CT chest suggestive IFI | 9 (14) | 3 (8) |
| CT abdomen suggestive IFI | 0 (0) | 0 (0) |
| Transplant order | ||
| First transplant | 50 (76) | 27 (73) |
| Second transplant | 15 (23) | 10 (27) |
| Subsequent transplant | 1 (1) | 0 (0) |
Data are number (%) unless otherwise indicated.
Abbreviations : CAF, computed tomography of the chest and abdomen for fungus; HSCT, hematopoietic stem cell transplantation; IFI, invasive fungal infection; ANC, absolute neutrophil count; SD, standard deviation.