Table 2.
Serum lysosomal enzyme activities in a cat with MPS VII and normal controls
| Enzyme | Diseasea | Cat with MPS VII | Normal cats Mean ± SD (n = 10) | |
|---|---|---|---|---|
| Activityb | %c | |||
| Mucopolysaccharidoses | ||||
| α‐L‐iduronidase | MPS I | 31.9 | 215.5 | 14.8 ± 6.7 |
| N‐acetylgalactosamine‐4‐sulphatase | MPS VI | 17.4 | 175.8 | 9.9 ± 3.6 |
| β‐D‐glucuronidase | MPS VII | 0.0 | 0.0 | 269.5 ± 32.5 |
| Glycoproteinoses | ||||
| α‐mannosidase | α‐Mannosidosis | 3015 | 100.4 | 3002 ± 779 |
| α‐L‐fucosidase | α‐Fucosidosis | 98.7 | 97.5 | 101.27 ± 34.0 |
a
Disease corresponds to the specific abnormal function of the enzyme tested.
b
Specific activity: nM 4 MU/h/mL serum.
c
Percentage activity of healthy controls (based on the mean of 10 healthy cats).