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Schematic of the experimental treatment phases and timeline. CON-PF= Control pair fed; PTD-EAS= Moderate pyrithiamine–induced TD; PTD-MAS= Severe pyrithiamine–induced TD; CET = Chronic Ethanol Treatment; CET-PTD= Started on CET and after one-month exposed to moderate PTD-EAS; PTD-CET = treated with the moderate PTD-EAS and after recovery exposed to CET.
