Table I.

Effect of serologically incompatible (mismatched) transfusion of red blood cells (RBC) in patients with warm-type autoimmune haemolytic anaemia (AIHA).

Transfusion series (n)*	Patients (n.)	Effect of RBC transfusions
		Hb increase (g/dL)	LDH concentration (U/L)**
			Increased/n.	Decreased/n.
>10	9	0.3–4.3	(45–319)/4	(31–527)/5
8	3	1.8–2.9	0	(27–619)/3
6	4	1.7–3.5	(12)/1	(61–578)/3
5	2	1.2–4.9	0	(18–771)/2
4	1	2.1	(9)/1	0
3	3	0.7–4.6	(42–115)/2	(497)/1
2	7	0.2–7.1	(13–156)/6	(93)/1
1	3	1.4–2.3	0	(67–109)/3

^*Transfusion series ≥2 RBC concentrates.

^**If measured prior to and after transfusion.

All detectable alloantibodies were considered and serological incompatibility was only related to serum autoantibodies.

Prior to transfusion of RBC, all patients were receiving treatment with immunosuppressive drugs or treatment was started with prednisolone (initially 100–250 mg/day). Increases in haemoglobin concentration are presented in a range of maximum delta values from 0.2 to 7.1 g/dL. Increases (14 patients) and decreases (18 patients) in lactate dehydrogenase are presented as a range of maximum delta values from 9 to 319 U/L and 18 to 771 U/L, respectively. Hb: haemoglobin; LDH: lactate dehydrogenase.