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Typical APTT reaction curves of (A) normal subjects and (B) patients with mild haemophilia A with a double mutation.
0: APTT, 1st: first derivative curve, 2nd: second derivative curve. The Max2 value (dA/dt2) is marked with the dashed line; the arrow points to the subsequent peak of the second derivative curve.
Note: the scales on the right axes are not of the same magnitude.
APTT: activated partial thromboplastin time; Max2: maximum value of the second derivative curve.
