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. 2015 Oct 27;7:112. doi: 10.1186/s13073-015-0226-3

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© Lee et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Query and results page – two-hit hypotheses test. a The input query window shows the selections of COADREAD (cancer type), TP53 copy number (first target), and TP53 mutation (second target). b This panel shows the joint copy number status and mutation status for TP53—results from the query input are shown in (a). c The input query window shows the selections of COADREAD (cancer type), TP53 RNA-Seq (first target), and TP53 mutations from genomic sequencing (second target). d This panel shows the expression levels of TP53 in samples with and without mutations as called from the query input shown in (c)