Table 2.

Type, subtypes, and sources of clinical parameters used in elastic-net analysis. Eighteen total clinical parameters were included—availability of each clinical attribute is dependent on cancer type

Clinical parameter	Number of subtypes	Type	Subtypes	Number of cancer types	Source
Country	16	Categorical	US, Russia, Korea South, Italy, etc.	17	TCGA
Gender	2	Binary	male, female	18	TCGA
HistoType	by cancer type	Categorical	Ex) Intestinal/diffuse for stomach	10	TCGA
PriorMalignancy	2	Binary	yes, no	7	TCGA
FamilyHistory	by cancer type	Ordinal	0,1,2,3	1	TCGA
M-Status	2	Binary	M0, M1	15	TCGA
N-Status	4	Ordinal	N0, N1, N2, N3	18	TCGA
ClinicalStage	4	Ordinal	I, II, III, IV	16	TCGA
T-Status	5	Ordinal	T0, T1, T2, T3, T4,	18	TCGA
HistoGrade	3	Ordinal	Low, Intermediate, High	11	TCGA
SmokingHistory	4	Categorical	Current smoker, Lifelong Non-smoker, Current reformed smoker for >15 years, Current reformed smoker for ≤15 years	8	TCGA
MolecularSubtype	2	Categorical	CIN, GS, MSI, EBV	1	TCGA
MSIstatus	3	Ordinal	MSS, MSI-L, MSI-H	5	UCSC
PAM50clust	5	Categorical	Normal-like, Luminal A, Luminal B, Basal-like, HER2-enriched	1	UCSC
RPPAclustersBRCA	6	Categorical	ReacI, LumA/B, Basal, LumA, Her2, ReacII	1	UCSC
GeneExpSubtype	4	Categorical	Classical, Mesenchymal, Proneural, Neural	1	UCSC
TripleMarker	4	Categorical	TripleNegative, Her2Positive, Erpositive, TriplePositive	1	UCSC
EBV present	2	Binary	Positive, Negative	1	cBio

cBio cBio portal, EBV Epstein–Barr virus, GeneExpSubtype types based on gene expression in glioblastoma multiforme, HistoGrade histology grade, HistoType histological type, CIN chromosomal instability, GS genomically stable, MSIstatus microsatellite instability status, MSS Microsatellite stable, MSI-L Microsatellite instable-low, MSI-H Microsatellite instable-high, PAM50clust clusters based on PAM50, RPPAclustersBRCA clusters based on reverse phase protein array data, TCGA The Cancer Genome Atlas, UCSC University of California Santa Cruz cancer genome browser