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. 2015 Oct 28;15:488. doi: 10.1186/s12913-015-1145-0

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© Naidoo et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Testing in the LPA and Xpert-based TB diagnostic algorithms. High MDR-TB-risk presumptive cases refer to those with previous TB, an MDR-TB contact or from a congregate setting. In the LPA-based algorithm, only these cases were initially screened for drug susceptibility. Low MDR-risk presumptive TB cases would only be identified when 1^st-line TB treatment regimens failed. In the Xpert-based algorithm in comparsion, all presumptive TB cases were simultaneously screened for TB and rifampicn resistance using Xpert