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. 2015 Oct 27;10(10):e0141327. doi: 10.1371/journal.pone.0141327

Fig 1. The effect of guanfacine (A) and yohimbine (B) on body weight.

Fig 1

The change in body weight in control (standard diet) and diet-induced obese Wistar rats, treated for 30 days with the tested compounds; Control group—water; Diet-induced obesity control group—water; Yohimbine at 2 mg/kg b.w., i.p.; Yohimbine at 5 mg/kg b.w., i.p.; Guanfacine at 0.5 mg/kg b.w., i.p.; Guanfacine at 2 mg/kg b.w., i.p.; Significant to 1st day: *P<0.05, **P<0.01, ***P<0.001 (ONE-WAY ANOVA) or significant to control group (water): #P<0.05, ##P<0.01, ###P<0.001 (TWO-WAY ANOVA) or significant to diet-induced obesity control group (water): ^P<0.05, ^^P<0.01, ^^^P<0.001 (TWO-WAY ANOVA).