Table 4. The effect of studied compounds on the amount of intraperitoneal adipose tissue.

	Control	Diet-induced obesity control	Yohimbine 2 mg/kg b.w.	Yohimbine 5 mg/kg b.w.	Guanfacine 0.5 mg/kg b.w.	Guanfacine 2 mg/kg b.w.
Weight of intraperitoneal fat tissue [g]	15.5 ± 2.56	28.5 ± 2.28**	23.0 ± 1.49*	14.9 ± 1.30 ##	17.5 ± 1.14 ##	14.2 ± 2.59 ##
Percentage of body weight	3.90	6.17	5.14	3.49	4.13	3.95

Weight of intraperitoneal fat tissue after 30 days treated using the test compounds in Wistar rats on diet-induced obesity. Treatment: Diet-induced obesity control group—water; Yohimbine at 2 mg/kg b.w., i.p.; Yohimbine at 5 mg/kg b.w., i.p.; Guanfacine at 0.5 mg/kg b.w., i.p.; Guanfacine at 2 mg/kg b.w., i.p.;

*Significant vs. control group, P<0.05;

**Significant vs. control group, P<0.01;

^##Significant vs. diet-induced obesity control group, P<0.01.