Table 6. The effect of the tested compounds on cell viability, cell membrane damage, glucose utilization and lipolysis.
| Compound | Concentration of the compound | Cell viability | Cell membrane damage | Glucose utilization | Lipolysis |
|---|---|---|---|---|---|
| Yohimbine | 50 μM | 94.0 ± 2.99 | 95.3 ± 6.60 | 95.6 ± 5.60 | 100.0 ± 2.99 |
| 10 μM | 103.7 ± 1.46 | 102.7 ± 2.04 | 101.3 ± 1.63 | 100.0 ± 4.48 | |
| 1 μM | 97.0 ± 2.25 | 109.7 ± 1.47 | 118.1 ± 0.36 *** | 99.3 ± 4.97 | |
| Guanfacine | 50 μM | 82.7 ± 0.72 *** | 95.0 ± 8.47 | 102.0 ± 3.51 | 100.0 ± 3.53 |
| 10 μM | 103.0 ± 1.40 | 92.0 ± 0.65 | 103.9 ± 0.58 | 100.0 ± 1.82 | |
| 1 μM | 99.7 ± 3.19 | 104.7 ± 6.86 | 112.1 ± 4.76 ** | 103.0 ± 4.08 |
% of control, mean ± SEM;
**P<0.01;
***P<0.001, ONE-WAY ANOVA