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. 2015 Oct 27;10(10):e0141509. doi: 10.1371/journal.pone.0141509

Fig 6. Effects of MAPK inhibitors on Nrf2 and HO-1 protein expression induced by quercetin.

Fig 6

Cells were treated with quercetin (12.5μM, 7 h) together with different doses of (A, B, C) SB202190, inhibitor for p38MAPK, and (D, E, F) U0126, inhibitor for MEK1/2 and ERK1/2. Bar graphs represent Nrf2/actin and HO-1/actin ratios (means ± SEM of four independent experiments). Data were analyzed by one-way ANOVA followed by Bonferroni post-tests. *p<0.05, **p<0.01, ***p<0.001 vs. control (no quercetin, no inhibitor).