Table I.
Biological and anthropometric characteristics, thyroid function, and dose of levothyroxine in the groups of women studied
| Parameter | Premenopausal | Postmenopausal | RDA | ||
|---|---|---|---|---|---|
| Treated SCH (n = 45) | Untreated SCH (n = 58) | Treated SCH (n = 180) | Untreated SCH (n = 180) | ||
| Age [years] | 43.62 ±6.65 | 44.77 ±6.82 | 59.51 ±7.90 | 58.75 ±7.92 | |
| Age of menarche [years] | 12.46 ±1.32 | 12.74 ±1.54 | 12.61 ±1.50* | 13.04 ±1.55 | |
| Years since menopause | 10.91 ±7.91 | 9.87 ±8.13 | |||
| BMI [kg/m2] | 27.02 ±6.39 | 26.58 ±4.39 | 28.53 ±4.55 | 27.75 ±4.27 | |
| Trunk lean mass [kg] | 24.42 ±2.56 | 23.93 ±2.03 | 23.75 ±2.09 | 23.39 ±2.00 | |
| Trunk fat mass [kg] | 11.23 ±5.48 | 11.82 ±4.22 | 13.09 ±1.10 | 12.19 ±3.93 | |
| Trunk fat% | 30.14 ±8.64 | 31.93 ±7.07 | 34.69 ±6.63 | 33.48 ±6.54 | |
| T4 dose/day [µg] | 90.88 ±42.59 | 86.35 ±34.11 | |||
| TSH [mU/l] | 1.38 ±0.29 | 6.72 ±1.42* | 1.19 ±0.17 | 8.8 ±1.7* | |
| FT4 [ng/dl] | 1.09 ±1.10 | 0.98 ±0.74 | 1.18 ±0.54 | 1.19 ±0.21 | |
| Calories/day | 2245.84 ±643.28 | 2076.56 ±410.82 | 2100.48 ±616.66 | 2172.07 ±580.24 | 2265 |
| Carbohydrates [g] | 271.56 ±104.77 | 273.33 ±73.97 | 260.89 ±94.13 | 265.73 ±80.86 | 330 |
| Fat [g] | 86.58 ±30.59* | 71.51 ±19.50 | 74.99 ±30.93 | 80.12 ±32.49 | 90 |
| Protein [g] | 93.15 ±38.64 | 83.34 ±18.31 | 91.28 ±31.85 | 95.86 ±36.77 | 47 |
| Protein/weight [g/kg] | 1.44 ±0.65 | 1.27 ±0.34 | 1.36 ±0.55 | 1.48 ±0.61 | 0.8 |
| Calcium [mg/day] | 1045.27 ±453.92 | 1049.40 ±461.59 | 1061.71 ±450.89 | 1128.47 ±471.17 | 800 |
| Phosphorus [mg/day] | 1407.66 ±504.49 | 1338.88 ±356.17 | 1387.53 ±508.05 | 1487.48 ±571.46 | 800 |
BMI – Body mass index, RDA – recommended dietary allowances
*
p < 0.01, compared with the respective untreated group.