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. 2015 Oct 12;11(5):1081–1094. doi: 10.5114/aoms.2015.54865

Table II.

Effect of ALA, DHA, EPA, LA, AA, GLA and 5-FU on relative gene expression of Bcl-2, Bax, and Human 18S in LoVo and RKO cells in vitro

LoVo treatment LoVo % survival Bcl-2 (% of CK) Bax (% of CK) RKO treatment RKO % survival Bcl-2 (% of CK) Bax (% of CK)
Control 1.00 ±0.05A 1.00 ±0.01a 1.00 ±0.07d Control 1 ±0.03A 1.00 ±0.02b 1.00 ±0.06c’
ALA 150 μm 0.63 ±0.01B 0.42 ±0.05c 2.20 ±0.09b’ ALA 140 μm 0.45 ±0.08B 0.52 ±0.04c 1.37 ±0.12b’
DHA 150 μm 0.63 ±0.08B 0.68 ±0.06b 1.15 ±0.11d’ DHA 120 μm 0.48 ±0.09B 1.30 ±0.14a 1.65 ±0.15b’
EPA 150 μm 0.70 ±0.05B 0.64 ±0.04b 1.22 ±0.07d’ EPA 120 μm 0.50 ±0.05B 0.70 ±0.08c 1.43 ±0.06b’
LA 150 μm 0.69 ±0.03B 0.70 ±0.02b 1.59 ±0.14c’ LA 120 μm 0.50 ±0.05B 0.65 ±0.07c 1.49 ±0.09b’
AA 150 μm 0.68 ±0.03B 0.37 ±0.02c 1.17 ±0.13d’ AA 120 μm 0.49 ±0.14B 0.72 ±0.05c 1.65 ±0.15b’
GLA 300 μm 0.63 ±0.06B 0.43 ±0.02c 1.96 ±0.19b’ GLA 200 μm 0.52 ±0.04B 0.57 ±0.09c 0.81 ±0.11c’
5-FU 10 μm 0.63 ±0.03B 0.69 ±0.06b 3.54 ±0.01a’ 5-FU 0.4 μm 0.42 ±0.05B 0.74 ±0.10c 3.95 ±0.15a’

Values with different letters are significantly different (p < 0.05).