Table 2.
Cell numbers and neuronal densities (neurons/mm3) in the septal nuclei of patients with schizophrenia, patients with affective disorders, and the healthy control subjects.
| Cell number (mean, SD, CE) | Ncl. lateralis | Ncl. medialis (pars fimbrialis and pars intermedia) | Ncl. dorsalis |
|---|---|---|---|
| Volume cell density (mean, SD, CE) | |||
| Control subjects (N = 6) | 123.0 (81.4; 0.27) | 171.6 (85.7; 0.22) (N = 5) | 131.0 (87.8; 0.27) |
| 2032 (687; 0.14) | 1717 (684; 0.18) | 1711 (1373; 0.33) | |
| Patients with schizophrenia (N = 10) | 257.4 (243.3; 0.32) (N = 9) | 329.7 (374.1; 0.43) (N = 7) | 224.2 (299.6; 0.45) (N = 9) |
| 2891 (1939; 0.22) | 2863 (3452; 0.46) | 2110 (2389; 0.38) | |
| Patients with affective disorders (N = 6) | 168.2 (91.3; 0.22) | 165.4 (98.3; 0.27) (N = 5) | 238.0 (150.5; 0.26) |
| 2378 (1193; 0.20) | 1744 (730; 0.19) | 2856 (1281; 0.18) | |
| Two-group-comparisons | |||
| Aff. vs. Ctr. (U-test) | 0.48; 0.59 | 1.00; 1.00 | 0.24; 0.24 |
| SZ vs. Ctr. (U-test) | 0.18; 0.61 | 0.76; 0.88 | 0.69; 0.86 |
| SZ vs. Aff. (U-test) | 0.78; 0.78 | 0.88; 1.00 | 0.78; 0.22 |
| Three-group-comparisons | |||
| ANOVA Ctr./Aff./SZ (p-value) | 0.34; 0.54 | 0.46; 0.62 | 0.65; 0.57 |
| Levene's-test | 0.048; 0.071 | 0.036; 0.10 | 0.50; 0.44 |
| K–W-test Ctr./Aff./SZ | 0.38; 0.76 | 0.94; 0.97 | 0.56; 0.33 |
The data are presented as the mean, standard deviation (SD), and coefficient of error (CE). Please note that the number of patients with schizophrenia included in the data for the nuclei lateralis, medialis (pars fimbrialis and pars intermedia), and dorsalis data is less than the original number of patients with schizophrenia (in bold). In addition, the number of patients with affective disorders included in the nuclei medialis data is less than the original number of patients with affective disorders (in bold). K–W-test, Kruskal–Wallis-test; Ctr, Control subjects; SZ, Patients with schizophrenia; Aff, Patients with affective disorders; Ncl., nucleus. Shrinkage-corrected data are presented.