Table 4.
Transgenic plants used in the production of therapeutic antibodies.
| Target | Transgenic plants | Antibodies | Application and specificity | Reference |
|---|---|---|---|---|
| Virus | Soybean | IgG against HSV-2 | Treatment for HSV | [19] |
| Virus | Tobacco | IgG against rabies virus | Treatment for rabies virus | [10, 20] |
| Virus | Tobacco | IgG against Ebola virus | Treatment for Ebola virus | [21, 22] |
| Virus | Tobacco | IgG against HIV | Treatment for HIV | [23] |
| Virus | Tobacco | IgG against RSV | Treatment for RSV | [24] |
| Virus | Tobacco | IgG against WNV | Treatment for West Nile virus | [25] |
| Cancer | Tobacco | ScFv against CEA | Tumor marker and clinical test | [26] |
| Cancer | Rice | ScFv against CEA | Tumor marker and clinical test | [27] |
| Cancer | Cereals | ScFv against CEA | Tumor marker and clinical test | [28] |
| Cancer | Tobacco | IgG against tumor antigen Lewis Y | Treatment for breast cancer | [29] |
| Cancer | Tobacco | IgG against tumor antigen GA733-2 | Treatment for colon cancer | [18, 30] |
| Bacteria | Tobacco | IgA against S. mutans | Prevention of dental caries | [31, 32] |
| Bacteria | Tobacco | IgG against S. mutans | Prevention of dental caries | [33] |
| Bacteria | Tobacco | Hybrid IgA-G | Anthrax | [34] |
HSV: herpes simplex virus; HIV: human immunodeficiency virus; RSV: human respiratory syncytial virus; WNV: West Nile virus; and CEA: carcinoembryonic antigen.