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. 2015 Sep 3;5(4):609–620. doi: 10.1016/j.stemcr.2015.08.002

Figure 1.

Figure 1

Overview of Approach

Starting with an initial segmentation, cells are tracked through the image data and a lineage is obtained. The parent-daughter relationships in the lineage are validated by the human observer. The validated lineage is then used to refine the segmentation and tracking under supervision. This refine and then validate process is repeated for each image, achieving a significant reduction in the segmentation error rate.