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. 1993 Apr 15;90(8):3121–3123. doi: 10.1073/pnas.90.8.3121

Long-term depression: not so depressing after all.

R C Malenka 1
PMCID: PMC46250  PMID: 8386364

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Selected References

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  1. Abraham W. C., Goddard G. V. Asymmetric relationships between homosynaptic long-term potentiation and heterosynaptic long-term depression. Nature. 1983 Oct 20;305(5936):717–719. doi: 10.1038/305717a0. [DOI] [PubMed] [Google Scholar]
  2. Aniksztejn L., Ben-Ari Y. Novel form of long-term potentiation produced by a K+ channel blocker in the hippocampus. Nature. 1991 Jan 3;349(6304):67–69. doi: 10.1038/349067a0. [DOI] [PubMed] [Google Scholar]
  3. Aroniadou V. A., Teyler T. J. The role of NMDA receptors in long-term potentiation (LTP) and depression (LTD) in rat visual cortex. Brain Res. 1991 Oct 18;562(1):136–143. doi: 10.1016/0006-8993(91)91197-9. [DOI] [PubMed] [Google Scholar]
  4. Artola A., Bröcher S., Singer W. Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex. Nature. 1990 Sep 6;347(6288):69–72. doi: 10.1038/347069a0. [DOI] [PubMed] [Google Scholar]
  5. Bienenstock E. L., Cooper L. N., Munro P. W. Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex. J Neurosci. 1982 Jan;2(1):32–48. doi: 10.1523/JNEUROSCI.02-01-00032.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bliss T. V., Collingridge G. L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 1993 Jan 7;361(6407):31–39. doi: 10.1038/361031a0. [DOI] [PubMed] [Google Scholar]
  7. Bliss T. V., Lomo T. Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J Physiol. 1973 Jul;232(2):331–356. doi: 10.1113/jphysiol.1973.sp010273. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Bortolotto Z. A., Collingridge G. L. Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus. Neuropharmacology. 1993 Jan;32(1):1–9. doi: 10.1016/0028-3908(93)90123-k. [DOI] [PubMed] [Google Scholar]
  9. Bröcher S., Artola A., Singer W. Intracellular injection of Ca2+ chelators blocks induction of long-term depression in rat visual cortex. Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):123–127. doi: 10.1073/pnas.89.1.123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Christofi G., Nowicky A. V., Bolsover S. R., Bindman L. J. The postsynaptic induction of nonassociative long-term depression of excitatory synaptic transmission in rat hippocampal slices. J Neurophysiol. 1993 Jan;69(1):219–229. doi: 10.1152/jn.1993.69.1.219. [DOI] [PubMed] [Google Scholar]
  11. Daniel H., Hemart N., Jaillard D., Crepel F. Coactivation of metabotropic glutamate receptors and of voltage-gated calcium channels induces long-term depression in cerebellar Purkinje cells in vitro. Exp Brain Res. 1992;90(2):327–331. doi: 10.1007/BF00227245. [DOI] [PubMed] [Google Scholar]
  12. Dudek S. M., Bear M. F. A biochemical correlate of the critical period for synaptic modification in the visual cortex. Science. 1989 Nov 3;246(4930):673–675. doi: 10.1126/science.2573152. [DOI] [PubMed] [Google Scholar]
  13. Dudek S. M., Bear M. F. Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4363–4367. doi: 10.1073/pnas.89.10.4363. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Fujii S., Saito K., Miyakawa H., Ito K., Kato H. Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices. Brain Res. 1991 Jul 26;555(1):112–122. doi: 10.1016/0006-8993(91)90867-u. [DOI] [PubMed] [Google Scholar]
  15. Grover L. M., Teyler T. J. Two components of long-term potentiation induced by different patterns of afferent activation. Nature. 1990 Oct 4;347(6292):477–479. doi: 10.1038/347477a0. [DOI] [PubMed] [Google Scholar]
  16. Hirsch J. C., Crepel F. Blockade of NMDA receptors unmasks a long-term depression in synaptic efficacy in rat prefrontal neurons in vitro. Exp Brain Res. 1991;85(3):621–624. doi: 10.1007/BF00231747. [DOI] [PubMed] [Google Scholar]
  17. Hirsch J. C., Crepel F. Postsynaptic calcium is necessary for the induction of LTP and LTD of monosynaptic EPSPs in prefrontal neurons: an in vitro study in the rat. Synapse. 1992 Feb;10(2):173–175. doi: 10.1002/syn.890100211. [DOI] [PubMed] [Google Scholar]
  18. Huang Y. Y., Malenka R. C. Examination of TEA-induced synaptic enhancement in area CA1 of the hippocampus: the role of voltage-dependent Ca2+ channels in the induction of LTP. J Neurosci. 1993 Feb;13(2):568–576. doi: 10.1523/JNEUROSCI.13-02-00568.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Kato N. Dependence of long-term depression on postsynaptic metabotropic glutamate receptors in visual cortex. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3650–3654. doi: 10.1073/pnas.90.8.3650. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Kauer J. A., Malenka R. C., Nicoll R. A. NMDA application potentiates synaptic transmission in the hippocampus. Nature. 1988 Jul 21;334(6179):250–252. doi: 10.1038/334250a0. [DOI] [PubMed] [Google Scholar]
  21. Konnerth A., Dreessen J., Augustine G. J. Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7051–7055. doi: 10.1073/pnas.89.15.7051. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Kullmann D. M., Perkel D. J., Manabe T., Nicoll R. A. Ca2+ entry via postsynaptic voltage-sensitive Ca2+ channels can transiently potentiate excitatory synaptic transmission in the hippocampus. Neuron. 1992 Dec;9(6):1175–1183. doi: 10.1016/0896-6273(92)90075-o. [DOI] [PubMed] [Google Scholar]
  23. Levy W. B., Steward O. Synapses as associative memory elements in the hippocampal formation. Brain Res. 1979 Oct 19;175(2):233–245. doi: 10.1016/0006-8993(79)91003-5. [DOI] [PubMed] [Google Scholar]
  24. Linden D. J., Connor J. A. Participation of postsynaptic PKC in cerebellar long-term depression in culture. Science. 1991 Dec 13;254(5038):1656–1659. doi: 10.1126/science.1721243. [DOI] [PubMed] [Google Scholar]
  25. Linden D. J., Dickinson M. H., Smeyne M., Connor J. A. A long-term depression of AMPA currents in cultured cerebellar Purkinje neurons. Neuron. 1991 Jul;7(1):81–89. doi: 10.1016/0896-6273(91)90076-c. [DOI] [PubMed] [Google Scholar]
  26. Lisman J. A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proc Natl Acad Sci U S A. 1989 Dec;86(23):9574–9578. doi: 10.1073/pnas.86.23.9574. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Lynch G. S., Dunwiddie T., Gribkoff V. Heterosynaptic depression: a postsynaptic correlate of long-term potentiation. Nature. 1977 Apr 21;266(5604):737–739. doi: 10.1038/266737a0. [DOI] [PubMed] [Google Scholar]
  28. Lynch G., Larson J., Kelso S., Barrionuevo G., Schottler F. Intracellular injections of EGTA block induction of hippocampal long-term potentiation. Nature. 1983 Oct 20;305(5936):719–721. doi: 10.1038/305719a0. [DOI] [PubMed] [Google Scholar]
  29. Malenka R. C., Kauer J. A., Zucker R. S., Nicoll R. A. Postsynaptic calcium is sufficient for potentiation of hippocampal synaptic transmission. Science. 1988 Oct 7;242(4875):81–84. doi: 10.1126/science.2845577. [DOI] [PubMed] [Google Scholar]
  30. Malenka R. C., Lancaster B., Zucker R. S. Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation. Neuron. 1992 Jul;9(1):121–128. doi: 10.1016/0896-6273(92)90227-5. [DOI] [PubMed] [Google Scholar]
  31. Malenka R. C. Postsynaptic factors control the duration of synaptic enhancement in area CA1 of the hippocampus. Neuron. 1991 Jan;6(1):53–60. doi: 10.1016/0896-6273(91)90121-f. [DOI] [PubMed] [Google Scholar]
  32. Mulkey R. M., Malenka R. C. Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus. Neuron. 1992 Nov;9(5):967–975. doi: 10.1016/0896-6273(92)90248-c. [DOI] [PubMed] [Google Scholar]
  33. Nakanishi S. Molecular diversity of glutamate receptors and implications for brain function. Science. 1992 Oct 23;258(5082):597–603. doi: 10.1126/science.1329206. [DOI] [PubMed] [Google Scholar]
  34. Sakurai M. Calcium is an intracellular mediator of the climbing fiber in induction of cerebellar long-term depression. Proc Natl Acad Sci U S A. 1990 May;87(9):3383–3385. doi: 10.1073/pnas.87.9.3383. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Sejnowski T. J. Storing covariance with nonlinearly interacting neurons. J Math Biol. 1977 Oct 20;4(4):303–321. doi: 10.1007/BF00275079. [DOI] [PubMed] [Google Scholar]
  36. Shibuki K., Okada D. Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum. Nature. 1991 Jan 24;349(6307):326–328. doi: 10.1038/349326a0. [DOI] [PubMed] [Google Scholar]
  37. Stanton P. K., Sejnowski T. J. Associative long-term depression in the hippocampus induced by hebbian covariance. Nature. 1989 May 18;339(6221):215–218. doi: 10.1038/339215a0. [DOI] [PubMed] [Google Scholar]
  38. Staubli U., Lynch G. Stable depression of potentiated synaptic responses in the hippocampus with 1-5 Hz stimulation. Brain Res. 1990 Apr 9;513(1):113–118. doi: 10.1016/0006-8993(90)91096-y. [DOI] [PubMed] [Google Scholar]
  39. Stent G. S. A physiological mechanism for Hebb's postulate of learning. Proc Natl Acad Sci U S A. 1973 Apr;70(4):997–1001. doi: 10.1073/pnas.70.4.997. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Stevens C. F. Neurobiology. A depression long awaited. Nature. 1990 Sep 6;347(6288):16–16. doi: 10.1038/347016a0. [DOI] [PubMed] [Google Scholar]
  41. Wickens J. R., Abraham W. C. The involvement of L-type calcium channels in heterosynaptic long-term depression in the hippocampus. Neurosci Lett. 1991 Sep 2;130(1):128–132. doi: 10.1016/0304-3940(91)90244-n. [DOI] [PubMed] [Google Scholar]
  42. Zheng F., Gallagher J. P. Metabotropic glutamate receptors are required for the induction of long-term potentiation. Neuron. 1992 Jul;9(1):163–172. doi: 10.1016/0896-6273(92)90231-2. [DOI] [PubMed] [Google Scholar]

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