Table 2. Clinical characteristics of oropharyngeal cancer patients with HPV infection.
| Patient NO. | HPV subtype | Sex | Age (y) | Tumor location | Histopathologic grade | TNM | Stage | Viral load # | E2/E6 rate |
|---|---|---|---|---|---|---|---|---|---|
| OPSCC-1 | HPV16 | M | 60 | Tonsil | Poorly differentiated | T3N2M1 | ⅣC | 359145 | 0.21 |
| OPSCC-2 | HPV16 | M | 41 | Tonsil | Moderately differentiated | T2N2M0 | ⅣA | 1885523 | 0.14 |
| OPSCC-3 | HPV16 | M | 54 | Tonsil | Poorly differentiated | T2N2M0 | ⅣA | 4083550 | 0.18 |
| OPSCC-4 | HPV16 | F | 70 | Tonsil | Moderately differentiated | T2N2M0 | ⅣA | 4664217 | 0.12 |
| OPSCC-5 | HPV16 | M | 50 | Tongue base | Well differentiated | T2N2M0 | ⅣA | 1819871 | 1.05 |
| OPSCC-6 | HPV16 | M | 60 | Tongue base | Poorly differentiated | T2N2M0 | ⅣA | 1333430 | 0 |
| OPSCC-7 | HPV16 | M | 58 | Tonsil | Poorly differentiated | T3N2M0 | ⅣA | 2115 | 0.35 |
| OPSCC-8 | HPV16 | F | 74 | Tonsil | Moderately differentiated | T2N2M0 | ⅣA | 14204321 | 0.12 |
| OPSCC-9 | HPV16 | M | 67 | Tonsil | Well differentiated | T2N1M0 | Ⅲ | 62634 | 0.02 |
| OPSCC-10 | HPV16 | M | 50 | Tonsil | Poorly differentiated | T2N1M0 | Ⅲ | 237 | 0.7 |
OPSCC, oropharyngeal squamous cell carcinoma
# E6 copies in 50 ng sample of DNA.