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. 2015 Oct 29;9:407. doi: 10.3389/fnins.2015.00407

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Copyright © 2015 Joppé, Hamilton, Cochard, Levros, Aumont, Barnabé-Heider and Fernandes.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BMP limits EGF-induced expansion of TAPs in vivo. Intracerebroventricular infusion paradigm (see Materials and Methods for details) (A). Brightfield immunohistochemistry for Ki67, with low magnification (upper) and high magnification (lower) images of each condition (B). Immunofluorescence for Olig2 (upper), DCX (middle) and pS6 (lower), each counterstained with Hoechst (C). Quantification of Ki67+ (D), Olig2+ (E), pS6+ (F), and DCX+ (G) SVZ cells (N = 4/group). Scale bars: (B) top: 250 microns, (B) bottom: 100 microns, (C): 25 microns. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, One-Way ANOVA (Tukey post-hoc test). Data are represented as mean ± SEM.