Figure 6. Effect of doxycycline on phenylalanine assemblies toxicity.

SH-SY5Y (A) and HeLa (B) cell lines were treated with 20 mM of Phe alone or after co-incubation with 25–50–100 μM of Doxy for 24 h. Cell viability was assessed by MTT assay. Values are mean ± SD of 12 samples from 4 different experiments. **p < 0.01, ***p < 0.001 vs Phe alone. One-way ANOVA followed by Dunnett’s multiple comparisons test.