Figure 4. Effects of dietary fiber on protein expressions of SREBP-1, FAS and ACC in C57BL/6J mice fed a high fat/cholesterol diet for 24 weeks.

The intensity of the bands was quantified by densitometric analysis and normalized with corresponding β-actin. Results are calculated as the mean ± SD of six mice. RC, reference chow diet group; HFC, high-fat/cholesterol diet group; OatWell, HFC plus 0.8% oat fiber group; Wheat, HFC plus 0.8% wheat bran fiber group; SREBP, sterol-regulatory element binding protein; FAS, fatty acid synthase; ACC, acetyl-CoA carboxylase. ^ap < 0.05, vs mice fed with RC diet. ^bp < 0.05, vs mice fed with HFC diet. ^cp < 0.05, vs mice fed with OatWell diet.