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. 2015 Oct 29;5:15575. doi: 10.1038/srep15575

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Copyright © 2015, Macmillan Publishers Limited

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MDBK cells were treated with CoPP (80 μM) 12 h, before BVDV (MOI of 0.1) infection, and then cells and culture supernatants were collected at the indicated times to detect intracellular HO-1, BVDV RNA (A) and protein (B), extracellular BVDV RNA (C) and virus titers (D) in the supernatants. Data are expressed as mean ± s.d. of three independent experiments, *P < 0.05, and ***P < 0.001.